高靈敏、經(jīng)過充分驗證的ELISA試劑盒，3小時內(nèi)即可得結(jié)果

血栓素A2（TXA2）參與血小板聚集、血管收縮和生殖功能，但在生理條件下的半衰期僅有37秒。血栓素B2（TXB2）是TXA2非酶水合的穩(wěn)定產(chǎn)物，因此體內(nèi)TXA2的產(chǎn)生通常通過檢測TXB2及其代謝物2,3-二酮TXB2來監(jiān)測。11-脫氫TXB2是血栓素B2（TXB2）在尿液和血漿中的主要代謝物，由11-OH-脫氫酶的脫氫作用產(chǎn)生。

Enzo Life Sciences提供的TXB2 ELISA試劑盒是一種比色競爭法試劑盒，可在3小時內(nèi)得到結(jié)果，在405 nm處讀取吸光值。在便捷的96孔板式檢測中，可通過檢測TXB2的產(chǎn)生來評估COX I的抑制情況。TXB2 ELISA試劑盒提供易于使用的、穩(wěn)定的液體彩色編碼試劑，可幫助減少實驗操作中的錯誤。欣博盛生物作為Enzo Life Sciences授權(quán)中國一級代理，可提供該產(chǎn)品，歡迎咨詢。

產(chǎn)品特點

◆ 高靈敏度，最-低可檢測10.54 pg/ml的TXB2

◆ 高通量，可在3小時內(nèi)檢測37份樣本（含復(fù)孔）

◆ 各種樣本類型在文獻(xiàn)中被廣泛引用，包括粘膜、組織、血清、血漿、尿液等

◆ 結(jié)果可靠，重復(fù)性好

產(chǎn)品信息

標(biāo)準(zhǔn)曲線示例

部分產(chǎn)品引用文獻(xiàn)

1. Chronic edible dosing of Δ9-tetrahydrocannabinol (THC) in nonhuman primates reduces systemic platelet activity and function: S.E. Reitsma, et al.; Am. J. Physiol. Cell Physiol. 322, 370 (2022)

2. Differential effects of cyclo-oxygenase 1 and 2 inhibition on angiogenesis inhibitor-induced hypertension and kidney damage: K.M. Mirabito Colafella, et al.; Clin. Sci. (Lond.) 136, 675 (2022)

3. Infection of Galleria mellonella (lepidoptera) larvae with the entomopathogenic fungus Conidiobolus coronatus (entomophthorales) induces apoptosis of hemocytes and affects the concentration of eicosanoids in the hemolymph: A.K. Wronska, et al.; Front. Physiol. 12, 774086 (2022)

4. Pharmacokinetic and pharmacodynamic profiles of a novel phospholipid-aspirin complex liquid formulation and low dose enteric-coated aspirin: results from a prospective, randomized, crossover study: F. Franchi, et al.; J. Thromb. Thrombolysis 54, 373 (2022)

5. Antioxidants and/or fish oil reduce intermittent hypoxia-induced inflammation in the neonatal rat terminal ileum: G. Mustafa, et al.; Prostaglandins Other Lipid Mediat. 155, 106565 (2021)

6. Effects of intestinal flora on the pharmacokinetics and pharmacodynamics of aspirin in high-altitude hypoxia: Y. Sun, et al.; PLoS One 15, e0230197 (2020)

7. Redundant role of ASK1-mediated p38MAPK activation in human platelet function: K.M. Sledz, et al.; Cell. Signal. 68, 109528 (2020)

8. Unexpected effects of long-term treatment with acetylsalicylic acid on late phase of pulmonary metastasis in murine model of orthotopic breast cancer: M. Smeda, et al.; PLoS One 15, e0230520 (2020)

9. A comparative study on the effect of argan oil versus fish oil on risk factors for cardio-vascular disease in high-fat-fed rats: A. Haimeur, et al.; Nutrition 57, 32 (2019)

10. Critical roles for the phosphatidylinositide 3-kinase isoforms p110β and p110γ in thrombopoietin-mediated priming of platelet function: S.F. Moore, et al.; Sci. Rep. 9, 1468 (2019)

11. Endothelin-1-Induced Microvascular ROS and Contractility in Angiotensin-II-Infused Mice Depend on COX and TP Receptors: C.S. Wilcox, et al.; Antioxidants (Basel) 8, E193 (2019)

12. Hyperglycemia enhances constriction of retinal venules via activation of the reverse-mode sodium-calcium exchanger: Y.L. Chen, et al.; Diabetes 68, 1624 (2019)

13. Ligustrazine inhibits platelet activation via suppression of the Akt pathway: L. Li, et al.; Int. J. Mol. Med. 43, 575 (2019)

14. Molecular profiling and functional analysis of macrophage-derived tumor extracellular vesicles: C. Cianciaruso, et al.; Cell Rep. 27, 3062 (2019)

15. Inhibitory Effects of an Orally Active Thromboxane A2 Receptor Antagonist, nstpbp5185, on Atherosclerosis in ApoE-Deficient Mice: S.W. Huang, et al.; Thromb. Haemost. 118, 401 (2018)

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